They would just be a wider tire, so you might rub when your turn sharp in either direction. Other than that they might flare out a little from the side so you might throw rocks every now and then.
I've got a glass pack on my 4.0 dcsb and my pipe has a turn down just where the bed starts. I CAN'T stand my glass pack anymore. I'm about to cut it off and just straight pipe it. Or put a thrush mad hot on it